Hormonal Control of Renal and Systemic Glutamine Metabolism

Hormonal control of renal and systemic glutamine metabolism.

Glutamine is the most abundant free amino acid in the human body. Recent studies indicate that it may be an important vehicle for interorgan nitrogen and carbon transport. However, relatively little is known about hormonal factors regulating its metabolism in humans. We review here our recent work on the effects of insulin, glucagon and epinephrine on plasma glutamine kinetics and its conversio...

Hormonal Control of Glucose Metabolism

Plasma glucose concentration is normally maintained within a narrow range despite wide fluctuations in the supply (meal) and demand (exercise) for nutrients. In adult humans, plasma glucose concentrations throughout a 24-hour period average 90 mg/ dl, with maximum values 60-90 minutes after meals, usually not exceeding 140 mg/ dl, and values during a moderate fast or exercise usually remaining ...

Glutamate transport asymmetry in renal glutamine metabolism.

d-Glutamate (Glu) was previously shown to block l-Glu uptake and accelerate glutaminase flux in cultured kidney cells [Welbourne, T. C., and D. Chevalier. Am. J. Physiol. 272 ( Endocrinol. Metab. 35): E367-E370, 1997]. To test whether d-Glu would be taken up by the intact functioning kidney and effect the same response in vivo, male Sprague-Dawley rats were infused withd-Glu (2.6 μmol/min), and...

Hormonal and nonhormonal control of glycogen metabolism.

Hormonal Control of Brown-Adipose-Tissue Metabolism

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